Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar, in fruits and vegetables
The mechanism of its action is based reducing the nitrogroup under the influence of the microorganism’s nitroreductases and the activity of the reduced nitroimidazole. The reduction products create compounds with DNA causing it to degrade, and disrupt the
Metronidazole is a member of the imidazole class of antibacterial agents and is classified therapeutically as an antiprotozoal and antibacterial agent. The intracellular targets of action of metronidazole on anaerobes are largely unknown. The 5-nitro grou
Ofloxacin is a synthetic 4-fluoroquinolone antibacterial agent with bactericidal activity against a wide range of Gram-negative and Gram-positive organisms
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